PMDD Treatment

Medically reviewed by Shahrzad Shadmani, PMHNP-BC, FNP-C

Premenstrual dysphoric disorder (PMDD) is more than a difficult few days before your period. It is a recognized psychiatric condition in which mood, anxiety and irritability become severe enough to disrupt work, relationships and daily life — and then lift again once your period starts. It is treatable, and it is frequently missed.

PMS or PMDD — what is the difference?

Premenstrual syndrome is common. PMDD is less common, affecting an estimated 1 to 5 percent of people who menstruate, and far more disruptive.

The difference is severity and pattern. In PMDD, symptoms reliably appear in the week before menstruation, begin to improve within a few days after it starts, and are minimal or absent in the week afterwards. At least one of the symptoms is a mood symptom: marked irritability or anger, depressed mood or hopelessness, anxiety or tension, or sudden shifts in mood.

Other symptoms can include losing interest in usual activities, difficulty concentrating, fatigue, changes in appetite or food cravings, sleeping too much or too little, feeling overwhelmed or out of control, and physical symptoms such as breast tenderness, bloating or joint pain.

How PMDD is diagnosed

Because PMDD is defined by its timing, diagnosis depends on tracking. We ask you to record your symptoms daily across at least two menstrual cycles.

That record does two jobs. It confirms whether your symptoms follow the cyclical pattern of PMDD, and it separates PMDD from an underlying depression or anxiety disorder that worsens before a period — which is common, and is treated differently.

We also look at the wider picture: thyroid function, other hormonal factors, sleep, and any current medications, because several conditions can mimic or amplify premenstrual symptoms.

Treatment options

SSRIs

Selective serotonin reuptake inhibitors are a first-line treatment for PMDD, and they often work more quickly for PMDD than they do for depression. Depending on your pattern, they can be taken every day or only during the second half of your cycle.

Hormonal options

Some hormonal contraceptives, including one formulation that has been studied specifically for PMDD, can reduce symptoms by smoothing out hormonal fluctuation. We coordinate with your OB/GYN or primary care clinician when this is part of the plan.

Therapy

Cognitive behavioral therapy can help with coping strategies, mood, and the strain PMDD places on relationships — alongside medication or on its own.

Sleep, stress and daily routine

Sleep, exercise and stress all influence premenstrual symptoms. They are part of the plan, not a substitute for treatment.

How care works at IPW Health

Your first appointment is a full psychiatric evaluation. From there we build a plan around your cycle, track how you respond over the next few cycles, and adjust. If hormonal treatment is part of the answer, we work with your gynecologist rather than treating mood and hormones as separate problems.

Care is available by secure telehealth across California, Oregon, Washington and Colorado, and in person at our Mission Viejo office.

Frequently asked questions

Do I need to have tracked my symptoms before my first appointment?

No. It helps if you have, but we will set you up with a simple way to track at your first visit.

Will I have to take medication every day?

Not necessarily. For some people, taking an SSRI only in the second half of the cycle is enough. We decide together based on your pattern and preferences.

Can premenstrual symptoms get worse with age?

They can. As hormone levels become more erratic in the years before menopause, premenstrual mood symptoms sometimes intensify. See perimenopause and menopause mental health.

Related: Women’s Health & Hormonal Psychiatry · Perimenopause & Menopause · Depression · Anxiety